Synbiotics, body weight and fat: early-stage discoveries

Synbiotics combine probiotics with prebiotics, such as inulin.

In the lab, mice that had synbiotics added to their diets for the first six weeks after birth had reduced body fat mass and lower body weight after an eight-week high-fat diet, compared to those that did not get synbiotics. The synbiotics group also had lower total cholesterol levels, and greater insulin sensitivity—the ability to use insulin to efficiently metabolize sugar—as adults. The gut microbiome in the synbiotics group also had higher levels of bifidobacterium as early as three weeks of age and continuing through 14 weeks.


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