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Trauma, burns, prolonged exercise and other stressors can deplete your body's glutamine stores. The more stress you're under, like that of a marathoner, the quicker you can deplete your glutamine supply.1
Also, during calorie restriction, your body might not synthesize glutamine as quickly as you need it. Consequently, researchers speculate that your body will use glutamine to fuel the brain and other body systems first. If any is left over, it will then be used to build muscle and maintain a strong immune system. That's where supplemental glutamine may help keep your tank topped off.
It's no mystery to most long-distance runners that within one week after race day you're likely to get sick. In fact, a recent study showed only 49% of those taking a placebo stayed healthy, while 81% of those taking glutamine stayed healthy.2
Why? Researchers are discovering that strenuous exercise can reduce the effectiveness of the immune system. While most of the body's cells use glucose for fuel, the immune system requires significant amounts of glutamine. This amino acid is important for the proliferation of lymphocytes and for several key functions of the macrophages. When you consume glutamine, you provide your body with a fuel it needs to stay healthy. This may allow you to train more frequently without as many of those frustrating down periods.*
NOTE: A study at Oxford University compared the health status of more than 150 runners. Half of the test subjects were given 5 grams of glutamine after a strenuous bout of exercise, while the other half took a placebo. Almost twice as many in the group with glutamine stayed healthy during the next 7 days compared to the placebo group.2 (Figure 1)
The human gut has two major divisions of beneficial bacteria called Firmicutes and Bacteriodetes. A few studies have uncovered a link between the ratio of these two divisions and body weight. Lower levels of Firmicutes are typically found in healthier, leaner people, while higher levels of Firmicutes are typically found in overweight individuals.
In a pilot study, 33 individuals with excess weight took 30 grams of L-glutamine or a placebo each day for two weeks. At the end of the study, the Firmicutes-to-Bacteriodetes ratio had decreased in the glutamine group by 33%, and it increased in the placebo group by 23%.3 (Figure 2)*
The researchers said the favorable changes to gut flora in the L-glutamine group were similar to those found in people on a weight loss program. Although L-glutamine may not cause weight loss, it may support overall gut health benefits.*
It's the best you can buy! Nothing else added. It meets or exceeds standards set forth by USP (the United States Pharmacopeia). Contains no wheat, gluten or soy.
This tasteless powder is easy to mix. Ideal for bodybuilders to add to creatine. Perfect for endurance athletes to mix with a carbohydrate drink before or after hard training or on race day.
Stir 1 level scoop (5 grams) of powder into 4-6 oz. of water or juice. Our L-Glutamine is a mild tasting white powder that mixes easily into liquids. Scoop enclosed.
Take 2 grams 1-2 times daily or as directed by a health professional.
Take 2-5 grams of L-glutamine 1-2 hours before workouts and another 2-5 grams after workouts.
Take 5 grams of L-glutamine right after strenuous exercise.
Selected Sources
1. Rowbottom, D. et al. "The emerging role of glutamine as an indicator of exercise stress and overtraining." Sports Medicine; 21(2): 80-97, 1996.
2. Castell, L. et al. "Does glutamine have a role in reducing infections in athletes?" European Journal of Applied Physiology; 73: 488-490, 1996.
3. Zambom de Souza, Alessandra Zanin et al. "Oral supplementation with L-glutamine alters gut microbiota." Nutrition; 31(6): 884-9, 2015.
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