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Alpha-lipoic acid helps combat oxidative stress

Early or subclinical hypothyroidism (SH) is an imbalance in thyroid hormones that causes low energy and fatigue. Doctors said that earlier studies linked SH to less-flexible blood vessels and elevated blood pressure. Because oxidative stress may be a factor in SH, researchers wanted to see if the antioxidant alpha-lipoic acid might help.

In one study, 40 women recently diagnosed with SH took alpha-lipoic acid or a placebo daily for three weeks. While there were no changes for the placebo group, those in the alpha-lipoic acid group had much lower levels of oxidative stress and greater blood-vessel flexibility compared to placebo and compared to the beginning of the study. Researchers also found a direct link: as levels of oxidative stress decreased, blood-vessel flexibility increased.

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