Greater Celandine

Also indexed as:Chelidonium majus
Greater Celandine: Main Image© Martin Wall
Botanical names:
Chelidonium majus

Parts Used & Where Grown

Greater celandine grows primarily in Europe and Asia, although it has been introduced in North America. The leaves and small yellow flowers of greater celandine are used as medicine. Although the roots and rhizomes of the plant have also been used medicinally, most clinical trials have used the above-ground parts of the plant collected at the time of flowering.1

  • Reliable and relatively consistent scientific data showing a substantial health benefit.
  • Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
  • For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

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This supplement has been used in connection with the following health conditions:

Used for AmountWhy
Indigestion, Heartburn, and Low Stomach Acidity
4 to 8 mg chelidonine in a standardized herbal extract three times per day2 stars[2 stars]
One study found that a standardized extract of greater celandine could relieve indigestion symptoms (such as abdominal cramping, sensation of fullness, and nausea) significantly better than placebo.
Refer to label instructions 1 star[1 star]
Herbalists sometimes recommend the use of topically applied greater celandine in treating warts.

Traditional Use (May Not Be Supported by Scientific Studies)

European herbal traditions regard greater celandine as a valuable remedy for the topical treatment of warts.2 It was also a folk remedy for cancer, gout, jaundice, and a variety of skin diseases. The famous French herbalist Maurice Mességué used greater celandine extensively in hand and foot baths and teas for many conditions, particularly those affecting the liver.3 In eastern Asia it was also valued as a treatment for peptic ulcer.4

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The information presented by Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2018.