Nutrition Express

Vitamin B12 Deficiency

Also indexed as:Pernicious Anemia
Your body relies on B12 for healthy blood. Too little of this vital vitamin can lead to anemia and other health issues. According to research or other evidence, the following self-care steps may be helpful.
  • Reliable and relatively consistent scientific data showing a substantial health benefit.
  • Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
  • For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary “Star-Rating” system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by some in the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

Vitamin B12
Consult a qualified healthcare practitioner3 stars[3 stars]
Vitamin B12, often given as an initial injection and then orally, may correct a deficiency.
Vitamin B12

See a doctor for evaluation3 stars[3 stars]
Taking vitamin B12 can help counteract deficiencies related to depression.
Vitamin B12

600 to 1,000 mcg daily3 stars[3 stars]
Taking vitamin B12 may help prevent and treat anemia. Deficiencies of iron, vitamin B12, and folic acid are the most common nutritional causes of anemia.
Vitamin B12

(Age-Related Cognitive Decline)
Consult a qualified healthcare practitioner2 stars[2 stars]
Improved brain function among seniors has been observed after correcting vitamin B12 deficiency with injections, but oral vitamin B12 has not been studied for ARCD. People with ARCD should be tested for vitamin B12 deficiency.
Vitamin B12

If deficient: 300 to1,000 mcg daily2 stars[2 stars]
Some studies have found people with thalassemia to be frequently deficient in vitamin B12, supplementing with the vitamin may help.
Vitamin B12

(Delayed Gastric Emptying, Helicobacter Pylori Infection, Indigestion, Heartburn, and Low Stomach Acidity)
1,000 mcg daily2 stars[2 stars]
Vitamin B12 may be beneficial for people with delayed emptying of the stomach in association with Helicobacter pylori infection and low blood levels of vitamin B12.
Vitamin B12

(Sickle Cell Anemia)
Consult a qualified healthcare practitioner2 stars[2 stars]
People with sickle cell anemia may be deficient in vitamin B12. Intramuscular vitamin B12 injections improved symptoms for patients in one study.
Vitamin B12

Refer to label instructions 1 star[1 star]
Vitamin B12 is found almost exclusively in foods of animal origin, which are restricted on the PKU diet. Supplementing with vitamin B12 may correct a deficiency.
Vitamin B12

(Dermatitis Herpetiformis)
Refer to label instructions 1 star[1 star]
Supplementing with vitamin B12 can counteract the nutrient deficiency that often occurs as a result of malabsorption.
Vitamin B-Complex

(Indigestion, Heartburn, and Low Stomach Acidity)
Refer to label instructions 1 star[1 star]
For people who have inadequate absorption of vitamin B12 due to low stomach acid, supplementing with vitamin B complex can help correct a deficiency.

Copyright © 2017 Healthnotes, Inc. All rights reserved.

Learn more about Healthnotes, the company.

The information presented by Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2017.