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Under normal circumstances, tyramine and dopamine are metabolized to their harmless metabolites by the enzyme monoamine oxidase (MAO). Drugs that inhibit MAO also inhibit the metabolism of tyramine and dopamine, leading to elevated levels of these substances in the bloodstream. Some people who suffer from migraines have found relief by eating a low-tyramine diet.
Excessive levels of tyramine can cause headache, palpitations, nausea, vomiting, and hypertensive crisis (dangerously high blood pressure).
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The information presented by Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2017.