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Early stage discoveries: Glucosamine reduced seizures

When nerves (neurons) in the hippocampus area of the brain become overexcited, seizures, including epilepsy, may develop.

Glucose is the major fuel for neurons, and it controls a protein that regulates neural excitability. The higher the protein level, the less excitable the neuron. Doctors thought that glucosamine might play a role in increasing neural protein levels. In the lab, glucosamine increased levels of the calming protein, which significantly reduced the sudden bursts of electrical activity associated with seizures.

 

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