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Aged garlic extract may reduce inflammation in obesity

Inflammation is the immune system’s natural response to help the body fight and heal from injury or bacterial infection. But low-level, chronic inflammation can lead to disease over the long term. Ancient civilizations used garlic to help maintain physical and mental health, and aging garlic stabilizes its sulfur compounds, allowing larger, more easily digestible doses. Extra weight can trigger inflammation, putting stress on body systems. 

In this study, 51 obese but otherwise healthy people, average age 45.6 years, took a placebo or 3,600 mg of aged garlic extract in three 1,200 mg doses per day. Doctors asked participants to maintain their regular diet and exercise schedule.

After six weeks, compared to placebo, the garlic group had significantly lower levels of two inflammatory factors: tumor necrosis factor alpha (TNF-alpha) and interleukin-6 (Il-6). The garlic group also had lower levels of LDL—the “bad” cholesterol. Discussing the findings, doctors said this may be the first study to test whether aged garlic extract may help prevent several chronic diseases linked to low-grade inflammation in obese adults.

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