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EGCG and down syndrome
Those with Down syndrome may have delayed physical growth, common facial features, and be cognitively immature. In this study, 84 people aged 16 to 34 with Down syndrome took a placebo or 4 mg of decaffeinated green tea epigallocatechin gallate (EGCG) per pound of body weight per day along with weekly online cognitive training.

After 12 months, compared to placebo, those taking EGCG were better able to remember and distinguish between objects, could more easily resist distraction, had greater ability to understand conceptual thinking, and could better function in social situations and use practical everyday skills. In reviewing brain scans, doctors also found greater connectivity between nerve cells.

Reference: Lancet Neurology; 2016, Vol. 15, No. 8, 801-10.
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