Resveratrol and bone density
Earlier lab studies found resveratrol protected against bone loss. In one of the first human trials, doctors said that metabolic syndrome can increase chances of bone loss, and gave 66 men with the syndrome a placebo, 1,000 mg or 150 mg of resveratrol in two divided doses per day.

After 16 weeks, compared to placebo, men who took the high-dose resveratrol had a 2.6 percent increase in lumbar spine bone mineral volume density, and a 16 percent increase in signs of bone formation. Researchers said resveratrol improved bone mineral density at the spine, primarily by stimulating mineralization, or bone formation.

Reference: Journal of Clinical Endocrinology & Metabolism; October, 2014, Published Online.
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