Folic acid may help hormone imbalance disorder and cholesterol levels

Many women of child-bearing age may inherit or develop a hormone imbalance disorder called polycystic ovary syndrome, or PCOS. Symptoms include irregular menstrual cycles, cystic ovaries, infertility, excess hair growth, obesity, and circulatory problems. Doctors thought folic acid might help.

In this study, 81 obese women with PCOS took 1 mg or 5 mg of folic acid, or a placebo, each day. After eight weeks, compared to placebo, both folic acid groups had less insulin resistance, lower total cholesterol, and lower levels of homocysteine, an inflammatory factor linked to heart disease. The high-dose folic acid group also saw a greater decline in LDL cholesterol levels while preserving HDL levels—the “bad” and “good” cholesterols, respectively.

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