Curcuminoids are effective in treating symptoms of OA of the knee
Doctors are seeking a safer alternative to standard non-steroidal anti-inflammatory drugs (NSAIDs) for treating pain in OA. Earlier studies had shown the anti-inflammatory phytochemicals in curcumin, called curcuminoids, were effective in protecting cartilage cells. In this study, 19 people with mild to moderate knee OA took 500 mg of curcuminoids three times per day, or a placebo.

At the start of the study, there were no significant differences in OA symptom scores, and participants in both groups were of similar age, gender, and body mass index. After six weeks, although stiffness was similar in both groups, the curcuminoids group saw greater relief from pain and improved physical function. Also, 84 percent of those in the curcuminoids group had stopped needing to take the NSAID naproxen for relieving pain, compared to 19 percent for placebo. Doctors said curcuminoids were safe and effective in treating symptoms of OA of the knee.

Reference: Phytotherapy Research; November, 2014, Vol. 28, No. 11, 1625-31.
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