Probiotics help reduce and keep weight off

Earlier studies have found overweight people have less healthy bacteria in the gut than those who are healthy-weight.

In this study, 125 overweight men and women ate a calorie-controlled diet for 12 weeks, followed by 12 weeks of weight maintenance. During the entire time, participants took lactobacillus rhamnosus or a placebo.

After the first 12 weeks, while there was no effect in men, women in the probiotics group had lost 10 pounds, compared to six pounds for placebo. Over the next 12 weeks, the placebo group reversed their progress while the women taking probiotics continued to lose more body weight and fat mass.Doctors don’t know why the men didn’t respond to probiotics, but suggest the dose may need to be higher or the study period increased. Probiotics may alter the permeability of the intestinal wall, keeping inflammatory molecules from entering the bloodstream and helping prevent a chain reaction leading to glucose intolerance, obesity, and type 2 diabetes, doctors said.

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