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Glucosamine and chondroitin reduced signs of systemic inflammation

Earlier lab studies found glucosamine and chondroitin have anti-inflammatory properties, but there are few studies on the effects of these nutrients in humans. In this study, doctors measured signs of inflammation in 217 men and women, aged 50 to 75, who were, or were not, taking glucosamine or chondroitin supplements.

Compared to those who did not take chondroitin supplements, men and women who took chondroitin an average of twice per day had 36 percent lower levels of the inflammatory factor— high-sensitivity C-reactive protein—than non-users. For glucosamine, compared to participants who did not take a supplement, regular glucosamine users had 28 percent lower levels of high sensitivity C-reactive protein than non-users. The researchers also measured a second inflammatory factor, prostaglandin E2, and found similar lower levels in both glucosamine and chondroitin users compared to non-users.

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