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Alpha-lipoic acid, curcumin and B vitamins may ease carpal tunnel syndrome

Carpal tunnel syndrome, where swollen tissue compresses the main forearm nerve as it passes through the wrist, is the most common nerve problem of the extremities. In this study, 180 adults undergoing nerve decompression surgery took alpha-lipoic acid, curcumin, and B-vitamins three months before and after surgery; or took the supplements only three months before surgery, or took no treatment. The twice-daily dose was 300 mg alpha-lipoic acid, 500 mg curcumin phytosome, and for the B-vitamins, 1.05 mg B1, 1.2 mg B2, 4.5 mg B5, and 1.5 mg B6.

While there were no differences between those that took no treatment and those that took supplements only before surgery, those that took supplements both before and after surgery, for a total of six months, had much less pain from wrist curling while asleep, and in a standard 60-second test for carpal tunnel syndrome, no tingling, numbness, or pain, 40 days after surgery.

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