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Folic acid may reduce cardiovascular problems
People with chronic kidney disease are more likely to have heart disease, and vice versa. In this review, doctors analyzed nine folic acid studies covering 8,234 people with kidney disease. Overall, the chances for developing cardiovascular disease was 10 percent lower in those who added folic acid to their diets compared to those who did not add folic acid.

Doctors found certain people benefited most from taking folic acid including smokers, those with end-stage kidney disease, those with chronically higher levels of the inflammatory factor homocysteine, and people who did not eat grains fortified with folic acid. As of 1998, the U.S. Food and Drug Administration required all manufacturers of enriched breads, cereals, flours, corn meals, pastas, rice, and other grain products to fortify them with folic acid.
 
Reference: Clinical Nutrition; 2013, Vol. 32, No. 5, 722-7
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