Glucosamine, chondroitin and quercetin reduced joint pain

Osteoarthritis (OA) is the most common cause of chronic pain and disability in older people, and involves progressive “wear and tear” deterioration of joint cartilage that is linked to oxidative stress.

In this study, 40 people with knee OA took a placebo or a supplement containing 1,200 mg of glucosamine, 60 mg of chondroitin, and 45 mg of quercetin glycosides per day.

After 16 weeks, compared to placebo, those who took the supplement had significantly less pain walking and climbing stairs. Doctors also found a small trend toward rebalancing the natural process of forming and breaking down a protein, type II collagen, that is the basis of cartilage.

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