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Vitamin D helped liver function in women with polycystic ovary syndrome

Polycystic ovary syndrome (PCOS) is a hormone imbalance— including excess male hormone levels—that changes menstruation, can impair fertility, and raises chances for metabolic syndrome and other physical and psychological conditions.

In this study, 40 women with PCOS took a placebo or 3,200 IU of vitamin D per day. After three months, vitamin D levels had more than tripled in the vitamin D group, and increased 1.5 times for placebo. Signs of systemic inflammation had decreased for vitamin D while remaining unchanged in the placebo group.

Doctors were interested in liver function, which can deteriorate in PCOS. When the liver is damaged, it releases excess amounts of a protein metabolizing enzyme, alanine transaminase, or ALT, into the bloodstream. ALT levels declined for the vitamin D group and increased for placebo. In women who were both overweight and deficient in vitamin D, those taking vitamin D showed fewer signs of liver scarring, and had improvements in liver function.

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