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Most people do not need to supplement histidine. Optimal levels for others remain unknown. Human research has used between 1 gram and 8 grams per day.
According to limited research, many people with rheumatoid arthritis have low levels of histidine. Taking histidine supplements might improve arthritis symptoms in some people.1
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The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires June 2014.