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Certain experts have questioned whether the current recommended blood levels and daily amounts of vitamin D are enough to best prevent disease and support health. This study looked at vitamin D levels across many countries and reviewed studies on the topic to explore whether higher blood levels of vitamin D, specifically 25-hydroxyvitamin D, were associated with a decreased incidence of death from common diseases such as heart disease, cancer, and respiratory infections.
Specifically, in this study, researchers reviewed the current scientific data on vitamin D to estimate whether higher blood levels of 25-hydroxyvitamin D (doubled from 54 nmol/L to 110 nmol/L) would reduce the death rate in the six global regions where vitamin D–sensitive diseases are prevalent.
The study authors comment, “Increasing . . . D levels is the most cost-effective way to reduce global mortality rates, as the cost of vitamin D is very low and there are few adverse effects from oral intake and/or frequent moderate UVB (ultraviolet-B) irradiance with sufficient body surface area exposed.” As the conclusions from this study are based primarily on preliminary research (that is, observational studies rather than randomized controlled trials), further research is needed to support these findings.
(Eur J Clin Nutr 2011; 1–11,doi:10.1038/ejcn.2011.68)
Jane Hart, MD, board-certified in internal medicine, serves in a variety of professional roles including consultant, journalist, and educator. Dr. Hart, a Clinical Instructor at Case Medical School in Cleveland, Ohio, writes extensively about health and wellness and a variety of other topics for nationally recognized organizations, websites, and print publications. Sought out for her expertise in the areas of integrative and preventive medicine, she is frequently quoted by national and local media. Dr. Hart is a professional lecturer for healthcare professionals, consumers, and youth and is a regular corporate speaker.