Grapefruit Seed Extract

Grapefruit Seed Extract

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Grapefruit seed extract (GSE) is a substance extracted from grapefruit seeds.

Where is it found?

Grapefruit seed extract is available in liquid concentrate and in capsules and tablets.

Grapefruit seed extract has been used in connection with the following conditions (refer to the individual health concern for complete information):

Science Ratings Health Concerns
1Star

Irritable bowel syndrome

3Stars Reliable and relatively consistent scientific data showing a substantial health benefit.
2Stars Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
1Star For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support and/or minimal health benefit.

Who is likely to be deficient?

Grapefruit seed extract is not an essential nutrient and no deficiency states have been reported.

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How much is usually taken?

The typical recommendation for the liquid concentrate is 10–12 drops in 6–7 ounces of water one to three times daily. For capsules and tablets containing dried grapefruit seed extract, the usual recommendation is 100–200 mg one to three times daily.

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Are there any side effects or interactions?

No side effects are known. The effects of grapefruit seed extract during pregnancy and breast-feeding have not been sufficiently evaluated.

At the time of writing, there were no well-known drug interactions with grapefruit seed extract.

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