Adapalene Also indexed as: Differin
Adapalene is a vitamin A–related drug that is applied to the skin to treat acne.
Summary of Interactions with Vitamins, Herbs, and Foods
In some cases, an herb or supplement may appear in more than one category, which may seem contradictory. For clarification, read the full article for details about the summarized interactions.
| Depletion or interference | None known |
| Side effect reduction/prevention | None known |
| Supportive interaction | None known |
| Reduced drug absorption/bioavailability | None known |
| Adverse interaction | None known |
An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.
Interaction with Foods and Other Compounds
Topical application of adapalene may cause skin irritation in some individuals. This irritation can be worsened when alcohol, astringents, spices, and lime are also applied to the area.1 Sensitive individuals should use caution when using adapalene and other topical compounds.
References (To view, roll mouse over the "References" heading; to hide, click on the heading)
1. Sifton DW, ed. Physicians Desk Reference. Montvale. NJ: Medical Economics Company, Inc., 2000, 1104–5.
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The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires February 2010.
