Supports Weight Management and Metabolic Wellness*
Fat cells (adipocytes) secrete a hormone called leptin that tells our brain we have eaten enough.52 Leptin can also facilitate the breakdown of stored triglycerides in our adipocytes via the process of lipolysis. Heavy individuals have startlingly high blood levels of leptin, indicating that their cells have become resistant to the leptin that is supposed to prevent them from putting on so many fat pounds.
An extract from an African mango called Irvingia gabonensis has been shown to help support leptin sensitivity in overweight people. In a recently published study, irvingia demonstrated beneficial effects upon leptin blood levels, followed by weight loss and inches off the waistline.48,53 In addition to supporting healthy leptin sensitivity, irvingia has demonstrated the following beneficial effects on key aspects of metabolism:
Glycerol-3-phosphate dehydrogenase is an enzyme involved in the complex biochemical process that converts ingested starch and sugar calories to stored body fat. Irvingia has been shown in studies involving fat cells to reduce the activity of glycerol-3-phosphate dehydrogenase,48,54 which may help reduce the impact of starch and sugar calories on body fat.
Scientific research on fat cells suggests that irvingia has alpha-amylase-inhibiting properties 55 (like InSea2® and Phaseolus vulgaris) which can help support a slowing of the rate of carbohydrate absorption from the intestines and a reduction of the caloric impact of starchy and sugary foods.54
Adiponectin is a hormone involved in helping to maintain insulin sensitivity on the membranes of energy-producing cells. Big fat cells produce less adiponectin, and overweight people need to be especially concerned about maintaining healthy levels of adiponectin to support insulin sensitivity and metabolic fitness. Scientific data suggests that irvingia helps support healthy adiponectin levels.53
Based on impressive human clinical data that irvingia supports weight loss of over 20 pounds on average in 10 weeks,47 this standalone extract of Integra-Lean® African Mango Irvingia is also available to help promote optimal weight.
47. Lipids Health Dis. 2009 Mar 2;8:7.;Prog Histochem Cytochem. 2010 Sep;45(3):143-200.48. Progress in Obesity Research. John Libbey & Company, Ltd., 1990:507-14.
49. Eur J Pharmaceut Biopharmaceut. 2009;72:453-62.
50. Agr Biol Chem. 1975;39(2):301-12.
51. U.S. Patent 3,856,945
52. U.S. Patent 3,928,322
53. U.S. Patent 3,973,008
54. U.S. Patent 3,767,424
55. Int J Obes. 1984;8(4):289-93.
Take one (1) capsule twice daily with or without food, or as recommended by a healthcare practitioner.
Integra-Lean Irvingia is protected by U.S. Patent No. 7,537,790. Other patents pending. IGOB-131 proprietary extract is a registered trademark of Gateway Health Alliances, Inc.
|1 Capsule Contains:|
Serving Price: $0.35
Price Per Capsule: $0.35
Order by Phone 800-338-7979 24 hours | Customer Service 800-754-8000
Information provided on this site is solely for informational purposes only. It is not a substitute for professional medical advice. Do not use this information for diagnosing or treating a health problem or disease, or prescribing of any medications or supplements. Only your healthcare provider should diagnose your healthcare problems and prescribe treatment. None of our statements or information, including health claims, articles, advertising or product information have been evaluated or approved by the United States Food and Drug Administration (FDA). The products or ingredients referred to on this site are not intended to diagnose, treat, cure or prevent any disease. Please consult your healthcare provider before starting any supplement, diet or exercise program, before taking any medications or receiving treatment, particularly if you are currently under medical care. Make sure you carefully read all product labeling and packaging prior to use. If you have or suspect you may have a health problem, do not take any supplements without first consulting and obtaining the approval of your healthcare provider. California Consumers – Proposition 65 requires sellers to notify California consumers of substances that are in many foods, plants, herbs and supplements with the following warning. WARNING: These products contain chemicals known to the State of California to cause birth defects or other reproductive harm.©2000-2015 Nutrition Express Corporation. All rights reserved.