Earlier short-term studies found omega-3s affected blood clotting differently in men and women. Doctors wanted to see if these effects would continue when taking omega-3s longer term. In the study, 94 healthy men and women took a placebo or 1,000 mg EPA with 200 mg DHA, or 1,000 mg DHA with 200 mg EPA, per day.
After four weeks, overall for men and women compared to placebo, the tendency to form blood clots was 12 and 15 percent lower for EPA and DHA, respectively. Looking at men and women separately, doctors found women benefited most from DHA while men responded best to EPA, both experiencing about an 18 percent improvement.