In osteoarthritis (OA), turmeric relieved pain and improved knee function, Pycnogenol cut inflammation, older men with good vitamin D levels had less OA, and, in rheumatoid arthritis, probiotics reduced pain and inflammation, several new studies reveal.
Doctors in an OA study said that long-term use of non-steroidal anti-inflammatory drugs (NSAIDs) for pain can cause serious side effects. After stopping pain medications for a week, 107 people, aged at least 50, with pain and stiffness from OA of the knee, took 400 mg of ibuprofen twice per day or 500 mg of turmeric curcuminoids four times per day. After six weeks, neither group had serious side effects and the turmeric group had less pain than the ibuprofen group when climbing stairs.
Doctors in an inflammation study explained that Pycnogenol works differently than NSAIDs to reduce pain. Six healthy participants took 150 mg of Pycnogenol per day for five days. Blood samples taken before and after supplementation showed that Pycnogenol blocked two pro-inflammatory enzymes scientists believe are the root cause of inflammatory pain.
In another OA study, researchers measured vitamin D levels in 1,104 men, average age 77, and followed up for five years. Men with vitamin D blood levels of 30 nanograms per milliliter or less were twice as likely to have OA of the hip than men with higher vitamin D levels.
In a rheumatoid arthritis (RA) study, 45 men and women with RA took a probiotics supplement or a placebo along with their standard pain medication. The probiotics supplement contained Bacillus coagulans, green tea extract, MSM, vitamins A, B, C, D, E, folic acid, and selenium. After 60 days, compared to placebo, the probiotics group reported much less pain, had fewer signs of inflammation (C-reactive protein), could better walk two miles, reach, and participate in daily activities.