Low levels of B-vitamins and trace minerals needed for synthesis of CoQ10 are one cause of low levels. Another cause is increased demand for CoQ10 to neutralize environmental toxins and free radicals generated during vigorous physical activity. Using statin drugs to treat high cholesterol further depletes stores of CoQ10. Finally, levels of CoQ10 naturally fall as one ages and this may contribute to several chronic degenerative conditions including heart disease, cancer, immune disorders, periodontal disease, muscular dystrophy, infertility, and neurodegenerative diseases.Heart Health
Supplementation with CoQ10, a key factor in the production of ATP, in patients with end stage heart failure is vital.
Other maladies of the heart that may benefit from CoQ10 supplementation are angina (heart cramp), arrhythmia (irregular beat), high blood pressure, cardiomyopathy (damaged heart muscle), mitral valve prolapse, preventricular contractions (PVC), and recovery from heart surgery. Doctors who practice complementary medicine often include CoQ10 supplementation to increase energy to the heart, along with standard medical therapy.Cancer
In addition, Dr. Bruce Ames has shown that deficiencies of folic acid, niacin, vitamins B6, B12, C, E and the minerals iron and zinc, cause DNA damage that may lead to cancer and neurodegenerative diseases. Paradoxically, many of these nutrients are also required for synthesis of CoQ10. Even cancer treatments themselves can severely deplete CoQ10 reserves.Immune Disorders
Being a large fat-soluble molecule that can be difficult to absorb, the most effective supplement is soft gelatin capsules containing solubilized CoQ10. Dry gelatin capsules containing powdered CoQ10 are less bioavailable because they are not combined with fat like CoQ10 in softgel form. Always consume CoQ with some fat or use the softgel form which has been shown to be more bioavailable and is considered worth the premium price paid for them since the cost per milligram absorbed is actually less.
CoQ10 Typical Daily Dosages
30-100 mg General Health
90-160 mg Heavy Exercisers
60-160 mg Family History - Heart Problems
100-200 mg Mild Heart Problems.
200-300 mg If Taking Statin Drugs
300-360 mg Congestive Heart Problems
1,200 mg Those With Parkinson's
Dosages of CoQ10 vary according to one's need and family history of disease. Taking CoQ10 will not benefit the heart much if circulating levels of this vitamin-like nutrient are already adequate. However, as one ages, it is less likely the body can maintain adequate CoQ10 levels. CoQ10 is extremely safe, even taken over long periods of time.