In an attention deficit hyperactivity disorder (ADHD) study, 57 children, average age 9, took 1 mg of Pycnogenol per kilogram of body weight per day or a placebo for one month. Researchers measured stress hormones in the urine before and after the study and again 30 days later. At the end of the study, kids in the Pycnogenol group had fewer ADHD symptoms and fewer signs of adrenaline and the nerve stimulant dopamine in the urine compared to the start of the study. Thirty days after the study ended, both the ADHD symptoms and adrenaline and dopamine had returned to pre-study levels.
In another ADHD study, 61 adolescent kids took 1 mg of Pycnogenol per kilogram of body weight per day or a placebo for four weeks. Parents and teachers tested the kids’ attention and concentration after taking Pycnogenol for one month and again four weeks later. After one month, kids who had taken Pycnogenol had significantly fewer ADHD symptoms compared to the start of the study and compared to placebo. Thirty days after the study ended, ADHD symptoms had returned, leading researchers to conclude that Pycnogenol had reduced ADHD symptoms.
In an iron study, researchers measured iron levels in 1,641 U.S. toddlers, aged one to three, including 42 percent Hispanic, 28 percent white non-Hispanic and 25 percent black children. Kids most likely to be deficient in iron were Hispanic, overweight, had non-English-speaking parents or were not in daycare.