Intense, exhausting exercise produces oxygen free-radicals and inflammation that damage muscles. In one study, 20 athletes ran an ultra-endurance 31-mile mountain climb. One group took a placebo, and the other took 30 mg of CoQ10 two days before, 90 mg of CoQ10 the day before, and 30 mg one hour before the climb. Comparing measurements after the run to before, the placebo group had signs of inflammatory oxidative stress 100 percent higher, and the CoQ10 group had signs just 37.5 percent higher.
Doctors said taking CoQ10 before strenuous exercise decreases the oxidative stress and inflammation that damages muscles.