These flat brown spots in themselves are harmless, but can be a sign of other underlying problems. They are the result of free radical damage in skin cells. According to Roger J. Williams, Ph.D., the author of Nutrition Against Disease, these deposits are not just on the surface skin, but may also be found in the brain, heart, adrenal gland, and other parts of the body. According to Dr. Williams, they are directly linked to a lack of vitamin E, and all of the other antioxidants. It is especially important to take these valuable antioxidants before these "age or liver spots" begin to appear on your skin or for the prevention of new ones. Other factors leading to age spots include: poor diet and liver function, consuming oxidized oils and fats over a period of time, lack of exercise, and excessive exposure to the sun. So, stay out of the direct sun, and take all your antioxidants in adequate amounts.