Glucomannan: An Amazing New Fiber

Nutrition and disagreement are nearly one in the same. Just about every nutrient has been blamed for causing obesity or some other chronic disease. You have fat-a-phobics, the carb-counters, protein-bashers, vegetarians, and the like who all avoid certain foods because of their purported ill-effects.

One nutrient that just about everyone agrees is good for you is fiber, and for good reason. In fact, it is my belief the benefits of fiber have been far under-emphasized, in particular, the benefits of a soluble fiber called glucomannan from konjac root.

Glucomannan is a type of soluble fiber, which means it dissolves in water and forms a gel. Research has shown that in head to head comparisons, glucomannan has greater gel volume and viscosity properties compared to other soluble fibers like guar gum and pectin.(1) Therefore, glucomannan can be used at lower doses to effectively promote weight and fat loss, suppress appetite, control glucose and insulin surges, and lower cholesterol.

Chart"

Weight Loss / Appetite Suppressant

A number of placebo-controlled studies have shown that relatively small amounts of glucomannan (1 to 4 grams a day) enhance weight loss.(2-7) In one randomized, double-blind, placebo-controlled trial, subjects were assigned to consume 1 gram of glucomannan with 8 ounces of water one hour before breakfast, lunch and dinner and not to change their eating or exercise patterns. Subjects in the glucomannan group lost 5.5 pounds, whereas the placebo group gained 1.5 pounds after 8 weeks.(3)

Thus, the beneficial effects of glucomannan on weight loss do not appear to be dependent on the caloric content or distribution of the diet, which makes this supplement extremely versatile for a wide range of people consuming any diet (very low-carbohydrate, low-fat, high-protein, etc.).

Glucomannan works primarily by reducing appetite because of its powerful bulk-forming properties in the stomach. This in turn promotes a feeling of fullness and passively reduces the total amount of calories consumed.

Controlling Glucose and Insulin Surges

Perhaps even more important, the bulk-forming properties of glucomannan also delay the rate by which food exits the stomach and enters into the intestines for absorption. This reduces the rate of absorption of nutrients into the bloodstream and has tremendous health implications due in part to better control of glucose and insulin surges.

A large number of studies have consistently shown that glucomannan taken prior to or with a meal significantly reduces the glucose and insulin response by as much as one-half.(8-11) In other words, glucomannan effectively reduces the glycemic index of foods and meals and a large number of well-controlled studies have shown that high glycemic index diets are associated with increased risk for heart disease and diabetes.(12-13)

Thus, the simple addition of glucomannan to a meal would be predicted to have significant clinical benefits on risk of chronic disease, in particular those related to insulin resistance and diabetes.(14-15)

Lipid-Lowering Effects

In addition to enhancing weight loss, and glucose and insulin levels, glucomannan has been shown to have significant and consistent cholesterol-lowering effects in a large number of clinical studies.(2),(3),(16-20) The effects are potent even with small doses (less than 4 grams a day). For example, in a recent randomized, placebo-controlled, double-blind, cross-over clinical trial in diabetic subjects, glucomannan (3.6 grams per day) decreased LDL-cholesterol by 21%, improved the total cholesterol to HDL-cholesterol ratio by 16%, and decreased the fasting and 2-hour glucose levels by 23% and 28%, respectively.(20)

In summary, glucomannan is a highly viscous soluble fiber that has been widely used in the orient for hundreds of years. An impressive amount of research has shown that small amounts of glucomannan taken before or during meals leads to significant weight loss and consistent reductions in appetite, cholesterol, glucose, and insulin. These effects have been observed in a variety of healthy and clinical populations.

No serious side effects have been documented in any of the studies of glucomannan. It is evidence-based, well tolerated, stimulant-free, and easy to incorporate into the diet. Most users take it in a capsule form to achieve proper dosage levels of about 1,000 mg.

Although glucomannan has been shown to effectively enhance weight loss, the beneficial effects of its lipid-lowering properties and its effects on glucose and insulin are not dependent on losing weight. Thus the therapeutic applications of glucomannan extend well beyond weight loss to include individuals with glucose and insulin disturbances (e.g., insulin resistance, glucose intolerance, and type II diabetes), cholesterol and other lipid disorders, and those with combinations of these disorders such as metabolic syndrome.

Given the epidemic prevalence of obesity, cardiovascular disease, and diabetes, the potential value of glucomannan as a preventive and therapeutic adjunct to other lifestyle interventions (i.e., diet and exercise) is enormous. The value of soluble fibers in the diet for promoting health is without debate, and glucomannan beats them all.

References

  1. Garcia MJ, Charlez M, Fauli C, Del Pozo Carrascosa A, Ghirardi PE. Physiochemical comparison of the dietary fibers glucomannan, galactomannan, carboxymethylcellulose, pectin, and wheat bran. Curr Ther Res. 1988 June;43(6):1010-3.
  2. Reffo GC, Ghirardi PE, Forattini C. Glucomannan in hypertensive outpatients: pilot clinical trial. Curr Ther Res. 1988 July;44(1):22-7.
  3. Walsh DE, Yaghoubian V, Behforooz A. Effect of glucomannan on obese patients: a clinical study. Int J Obes. 1984;8(4):289-93.
  4. Livieri C, Novazi F, Lorini R. [The use of highly purified glucomannan-based fibers in childhood obesity] Pediatr Med Chir. 1992 Mar-Apr;14(2):195-8.
  5. Vita PM, Restelli A, Caspani P, Klinger R. [Chronic use of glucomannan in the dietary treatment of severe obesity] Minerva Med. 1992 Mar;83(3):135-9.
  6. Cairella M, Marchini G. [Evaluation of the action of glucomannan on metabolic parameters and on the sensation of satiation in overweight and obese patients] Clin Ter. 1995 Apr;146(4):269-74.
  7. Biancardi G, Palmiero, Ghirardi PE. Glucomannan in the treatment of overweight patients with osteoarthritis. Curr Ther Res. 1989 Nov;46(5):908-12.
  8. Doi K. Effect of konjac fibre (glucomannan) on glucose and lipids. Eur J Clin Nutr. 1995 Oct;49 Suppl 3:S190-7.
  9. Hopman WP, Houben PG, Speth PA, Lamers CB. Glucomannan prevents postprandial hypoglycaemia in patients with previous gastric surgery. Gut. 1988 Jul;29(7):930-4.
  10. Shima K, Tanaka A, Ikegami H, Tabata M, Sawazaki N, Kumahara Y. Effect of dietary fiber, glucomannan, on absorption of sulfonylurea in man. Horm Metab Res. 1983 Jan;15(1):1-3.
  11. Scalfi L, Coltorti A, D'Arrigo E, Carandente V, Mazzacano C, Di Palo M, Contaldo F. Effect of dietary fibre on postprandial thermogenesis. Int J Obes. 1987;11 Suppl 1:95-9.
  12. Jenkins DJ, Wolever TM, Taylor RH, Barker H, Fielden H, Baldwin JM, Bowling AC, Newman HC, Jenkins AL, Goff DV. Glycemic index of foods: a physiological basis for carbohydrate exchange. Am J Clin Nutr. 1981 Mar;34(3):362-6.
  13. Brand-Miller JC. Glycemic load and chronic disease. Nutr Rev. 2003 May;61(5 Pt 2):S49-55.
  14. McCarty MF. Glucomannan minimizes the postprandial insulin surge: a potential adjuvant for hepatothermic therapy. Med Hypotheses. 2002 Jun;58(6):487-90.
  15. Vuksan V, Sievenpiper JL, Xu Z, Wong EY, Jenkins AL, Beljan-Zdravkovic U, Leiter LA, Josse RG, Stavro MP. Konjac-Mannan and American ginsing: emerging alternative therapies for type 2 diabetes mellitus. J Am Coll Nutr. 2001 Oct;20(5 Suppl):370S-380S; discussion 381S-383S.
  16. Vuksan V, Jenkins DJ, Spadafora P, Sievenpiper JL, Owen R, Vidgen E, Brighenti F, Josse R, Leiter LA, Bruce-Thompson C. Konjac-mannan (glucomannan) improves glycemia and other associated risk factors for coronary heart disease in type 2 diabetes. A randomized controlled metabolic trial. Diabetes Care. 1999 Jun;22(6):913-9.
  17. Vuksan V, Sievenpiper JL, Owen R, Swilley JA, Spadafora P, Jenkins DJ, Vidgen E, Brighenti F, Josse RG, Leiter LA, Xu Z, Novokmet R. Beneficial effects of viscous dietary fiber from Konjac-mannan in subjects with the insulin resistance syndrome: results of a controlled metabolic trial. Diabetes Care. 2000 Jan;23(1):9-14.
  18. Arvill A, Bodin L. Effect of short-term ingestion of konjac glucomannan on serum cholesterol in healthy men. Am J Clin Nutr. 1995 Mar;61(3):585-9.
  19. Gallaher DD, Gallaher CM, Mahrt GJ, Carr TP, Hollingshead CH, Hesslink R Jr, Wise J. A glucomannan and chitosan fiber supplement decreases plasma cholesterol and increases cholesterol excretion in overweight normocholesterolemic humans. J Am Coll Nutr. 2002 Oct;21(5):428-33.
  20. Chen HL, Sheu WH, Tai TS, Liaw YP, Chen YC. Konjac supplement alleviated hypercholesterolemia and hyperglycemia in type 2 diabetic subjects--a randomized double-blind trial. J Am Coll Nutr. 2003 Feb;22(1):36-42.

 
Log In   |  Checkout  |  CartCart
My Account   My Cart    
Log In