A study from the Human Performance Laboratory at St. Cloud State University, St. Cloud, Minnesota, shows that the use of the dietary supplement of Phosphatidyl Serine (PS) has a positive effect on muscular stress following moderately intense, aerobic exercise by trained runners. "It is generally accepted that creatine kinase is an indicator of cell membrane damage and necrosis of the muscle fibers," says John Seifert, a principal investigator at St. Cloud. "Our work shows that PS supplementation results in significantly lower amounts of creatine kinase (CK) levels 24 hours after exercise. This implies that PS can help minimize muscle fiber damage caused by muscular stress."
Twelve trained runners ingested either 600 mg of PS, 300 mg of PS, or a placebo for 15 days, and then performed a 90-minute run on the 15th day in this double-blind, crossover study. Blood samples were collected at 30-minute intervals throughout the performance tests as well as 24 hours afterwards. There was a significant difference between the three treatments in the blood levels of CK in the runners. Twenty-four hours after the 90-minute runs, those receiving the placebo showed the highest average value of CK. Those receiving PS supplements had CK levels less than half as high.