Phosphatidylcholine (PC), dimethylaminoethanol (DMAE), and phosphatidylserine (PS) are needed to make acetylcholine, the neurotransmitter that is essential for proper thought and memory processes. If the supply of PC in the brain is inadequate, information storage and retrieval becomes inefficient, and impaired memory results. Studies reveal that sufficient concentrations of PC in the brain are best attained by supplementation rather than by diet.
DMAE has been found to enhance memory and learning capabilities.
PS comprises 70% of the brain's nerve tissue and is necessary for normal brain function. PS supplements are derived from lecithin.
Dr. Thomas Crook III studied 150 patients with memory problems, aged 50 to 75 years. He gave 75 of the patients 100 mg of PS three times per day for 12 weeks, and the other 75 received a placebo. All patients took regular neuro-psychological tests. Those taking PS scored 30% higher on tests of learning and memory, and those with the worst memory deficits benefited the most. "PS is not a magic bullet," said Dr. Crook. "It's not like you're 75 and take it and become 25. But it is the first thing we've ever seen of many, many compounds that does have a clear measurable effect, and that effect is about 12 years of rolling back the clock. I really firmly believe PS can roll back virtually all age-related memory impairment."